Available abstracts of recently published papers and articles by Iconix authors or about Iconix. In some cases, preprints, reprints, and supplemental data are available.

2008
M. Fielden et al, Inter-laboratory Evaluation of Genomic Signatures for Predicting Carcinogenicity in the Rat , Toxicological Sciences (2008).
( PDF available from Toxicological Sciences )

G. Natsoulis et al, The Liver Pharmacological and Xenobiotic Response Repertoire , Molecular Systems Biology (2008).
( Supplemental Data )

2006
A. Engelberg, The Use of Toxicogenomics in the Pharmaceutical and Biotechnology Industries , Iconix Pharmaceuticals, June 2006.
( Reprint available by mail )

M.R. Fielden et al, The state-of-the-art in predictive toxicogenomics , Current Opinion in Drug Discovery and Development (2006) 9(1): 84-91
( Reprint available by mail )

S. Tugendreich et al, NSAID-Induced Acute Phase Response is Due to Increased Intestinal Permeability and Characterized by Early and Consistent Alterations in Hepatic Gene Expression , Toxicologic Pathology (2006) 34(2): 168-79
( Reprint available by mail )

2005
R. Brennan et al, Iconix's new Illustrated Atlas of Rat Liver Pathology
( CD ROM including complete text and photographs )

B. Ganter et al, Development of a large-scale toxicogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action , Journal of Biotechnology (2005) 119: 219-44.
( Supplemental Material ) ( Reprint available by mail )

M.R. Fielden et al, A Gene Expression Signature that Predicts the Future Onset of Drug-Induced Renal Tubular Toxicity , Toxicological Pathology (2005) 33: 675-683.
( Supplemental Data ) ( Reprint available by mail )

M.R. Fielden et al, Preclinical Drug Safety Analysis by Chemogenomic Profiling in the Liver , American Journal of Pharmacogenomics (2005) 5: 161-171.

J.S. MacNeil, Genomics Goes Downstream , Genome Technology, July/August 2005.
( Reprint available as PDF by e-mail )

G. Natsoulis et al, Classification of a large microarray data set: Algorithm comparison and analysis of drug signatures , Genome Research (2005) 15: 724-736.
( Supplemental Data ) ( Reprint available by mail )

A.H. Roter, Large-scale integrated databases supporting drug discovery , Current Opinions in Drug Discovery & Development (2005) 8: 309-315.

K.L. Thompson et al, Use of a mixed tissue RNA design for performance assessments on multiple microarray formats , Nucleic Acids Research (2005) 33(22), e187

2004
K. Kolaja et al, The impact of toxicogenomics on preclinical development: from promises to realized value to regulatory implications , Preclinica (2004) 2: 122-129.